Patient-reported outcomes following abiraterone acetate plus prednisone added to androgen deprivation therapy in patients with newly diagnosed metastatic castration-naive prostate cancer (LATITUDE): an international, randomised phase 3 trial.
| Author | |
|---|---|
| Abstract | :  In the LATITUDE trial, addition of abiraterone acetate plus prednisone to androgen deprivation therapy (ADT) improved overall survival compared with placebos plus ADT in patients with newly diagnosed, high-risk, metastatic castration-naive prostate cancer. Understanding the effects of treatments on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) is important for treatment decisions; therefore we aimed to analyse the effects of ADT plus abiraterone acetate and prednisone versus ADT plus placebos on PROs and HRQOL in patients in the LATITUDE study. | 
| Year of Publication | :  2018 | 
| Journal | :  The Lancet. Oncology | 
| Date Published | :  2018 | 
| ISSN Number | :  1470-2045 | 
| DOI | :  10.1016/S1470-2045(17)30911-7 | 
| Short Title | :  Lancet Oncol | 
| Download citation |