Cardiac biomarkers of disordered eating: A case for decreased mean R wave amplitude.
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| Abstract | :  The purpose of this study was to identify cardiac biomarkers of disordered eating. Mean R wave amplitude (mV), mean T wave amplitude (mV), QRS interval (sec), QTc interval (sec), and Tpeak-Tend interval (sec) were assessed via electrocardiography among women with clinical (n = 53) and subclinical (n = 56) eating disorder symptoms versus asymptomatic controls (n = 32). QRS and QTc intervals were significantly longer and mean T and R wave amplitudes significantly lower among women with clinical symptoms compared to asymptomatic controls. QTc interval length was significantly longer and mean R wave amplitude was significantly lower among women with subclinical symptoms versus asymptomatic controls. Decreased mean R wave amplitude yielded a comparable effect size as QTc when differentiating between asymptomatic and subclinical groups and a larger effect size than QTc when differentiating between asymptomatic and clinical groups, representing a promising clinical biomarker. | 
| Year of Publication | :  2019 | 
| Journal | :  Psychiatry research | 
| Volume | :  272 | 
| Number of Pages | :  555-561 | 
| ISSN Number | :  0165-1781 | 
| URL | :  https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(18)31419-7 | 
| DOI | :  10.1016/j.psychres.2018.12.162 | 
| Short Title | :  Psychiatry Res | 
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