Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.
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Abstract | :
While monoclonal antibodies against tumor necrosis factor-α (TNFα) are effective in treating Crohn's disease (CD), approximately one-third of patients lose response. The mechanisms underlying this loss of response remain elusive. |
Year of Publication | :
2018
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Journal | :
Digestive diseases and sciences
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Date Published | :
2018
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ISSN Number | :
0163-2116
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DOI | :
10.1007/s10620-018-4932-8
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Short Title | :
Dig Dis Sci
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